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乳鐵蛋白抗體
  • 產(chǎn)品貨號(hào)：
    BN41925R
  • 中文名稱：
    乳鐵蛋白抗體
  • 英文名稱：
    Rabbit anti-Lactoferrin Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN41925R-50ul

    50ul

    ￥1486.00

    交叉反應(yīng)：Human(predicted:Sheep,Horse,Cow,Pig,Dog,Rat,Mouse) 推薦應(yīng)用：WB,Flow-Cyt,ELISA

  • BN41925R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human(predicted:Sheep,Horse,Cow,Pig,Dog,Rat,Mouse) 推薦應(yīng)用：WB,Flow-Cyt,ELISA

  • BN41925R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human(predicted:Sheep,Horse,Cow,Pig,Dog,Rat,Mouse) 推薦應(yīng)用：WB,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱Lactoferrin
中文名稱乳鐵蛋白抗體
別    名CKRX; GIG12; Growth inhibiting protein 12; HLF2; Homo sapiens chemokine receptor X; Kaliocin 1; Lactoferrin; Lactoferroxin A; Lactoferroxin B; Lactoferroxin C; Lactoferroxin-C; Lactotransferrin; LF; LTF; Neutrophil lactoferrin; Talalactoferrin alfa; Talalactoferrin; TRFL_HUMAN.  



研究領(lǐng)域腫瘤  心血管  細(xì)胞生物  免疫學(xué)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=0.2ug/test 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量76kDa
細(xì)胞定位細(xì)胞核 細(xì)胞漿 分泌型蛋白 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Lactoferrin:611-710/710 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.

Function:
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.
Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration.
Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors.
The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.
Isoform DeltaLf: transcription factor with antiproliferative properties and inducing cell cycle arrest. Binds to DeltaLf response element found in the SKP1, BAX, DCPS, and SELH promoters.

Subunit:
Monomer. Found in a complex with LTF, CLU, EPPIN and SEMG1.

Subcellular Location:
Isoform 1: Secreted. Isoform DeltaLf: Cytoplasm. Nucleus.

Post-translational modifications:
Isoform DeltaLf: Ubiquitinated at Lys-379 and Lys-391.

Similarity:
Belongs to the transferrin family.
Contains 2 transferrin-like domains.

SWISS:
P02788

Gene ID:
4057

Database links:

Entrez Gene: 4057 Human

Entrez Gene: 17002 Mouse

Entrez Gene: 301034 Rat

Omim: 150210 Human

SwissProt: P02788 Human

SwissProt: P08071 Mouse

Unigene: 529517 Human

Unigene: 282359 Mouse

Unigene: 218647 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

















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