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白介素-22抗體
  • 產(chǎn)品貨號：
    BN41841R
  • 中文名稱：
    白介素-22抗體
  • 英文名稱：
    Rabbit anti-IL22 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

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  • BN41841R-50ul

    50ul

    ￥1486.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Dog) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41841R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Dog) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41841R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Dog) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱IL-22
中文名稱白介素-22抗體
別    名Interleukin-22; Il22; Iltif; ILTIFa; MGC129416; MGC129417; IL-10-related T-cell-derived-inducible factor; IL-TIF; ILTIF; IL-TIF alpha; Interleukin-22a; IL-22a; IL 21; IL D110; IL TIF; IL21; IL22; ILD110; interleukin 21; MGC79382; MGC79384; TIFa; TIFIL 23; TIFIL-23; TIFIL23; zcyto18; Cytokine Zcyto18.  



研究領(lǐng)域免疫學(xué)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse,  (predicted: Rat, Dog, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg /test IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量17kDa
細胞定位分泌型蛋白 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human IL-22:35-179/179 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq].

Function:
Cytokine that contributes to the inflammatory response in vivo.

Subcellular Location:
Secreted.

Similarity:
Belongs to the IL-10 family.

SWISS:
Q9GZX6

Gene ID:
50616

Database links:

Entrez Gene: 50616 Human

Entrez Gene: 50929 Mouse

Entrez Gene: 500836 Rat

Omim: 605330 Human

SwissProt: Q9GZX6 Human

SwissProt: Q9JJY9 Mouse

Unigene: 287369 Human

Unigene: 103585 Mouse

Unigene: 195879 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

IL-22是白介素-10家族的成員,主要是由激活的T 淋巴細胞產(chǎn)生的一類重要的細胞因子,除了在Th17細胞中高表達之外，在NK和NKT等細胞中也有表達,在組織損傷修復(fù)以及牛皮癬、肝炎、肺炎、腸炎等慢性炎癥中發(fā)揮重要作用.IL-22是繼IL-6和IL-10之后又一個參與炎癥反應(yīng)和代謝調(diào)控的細胞因子，IL-22有可能成為干預(yù)脂肪肝發(fā)生發(fā)展的新方法。