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S100A13抗體
  • 產(chǎn)品貨號(hào)：
    BN41840R
  • 中文名稱：
    S100A13抗體
  • 英文名稱：
    Rabbit anti-S100A13 Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN41840R-50ul

    50ul

    ￥1486.00

    交叉反應(yīng)：Mouse,Human(predicted:Rabbit,Horse,Cow,Dog,Rat) 推薦應(yīng)用：IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41840R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Mouse,Human(predicted:Rabbit,Horse,Cow,Dog,Rat) 推薦應(yīng)用：IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41840R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Mouse,Human(predicted:Rabbit,Horse,Cow,Dog,Rat) 推薦應(yīng)用：IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱S100A13
中文名稱S100A13抗體
別    名Protein S100 A13; S100 calcium binding protein A13; S10AD_HUMAN; Protein S100-A13; S100 calcium-binding protein A13; S100a13.  
研究領(lǐng)域腫瘤  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse,  (predicted: Rat, Dog, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量11.5kDa
細(xì)胞定位細(xì)胞漿 分泌型蛋白 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human S100A13:51-98/98 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine.

Subunit:
Homodimer. Part of a copper-dependent multiprotein complex containing S100A13, FGF1 and SYT1. Interacts with FGF1 and SYT1.

Subcellular Location:
Cytoplasm. Secreted. Secretion is mediated by exposure to stress and requires copper ions.

Tissue Specificity:
Expressed in heart and skeletal muscle.

Similarity:
Belongs to the S-100 family.
Contains 1 EF-hand domain.

SWISS:
Q99584

Gene ID:
6284

Database links:

Entrez Gene: 6284 Human

Omim: 601989 Human

SwissProt: Q99584 Human

Unigene: 516505 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.