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Fas相關(guān)1因子抗體
  • 產(chǎn)品貨號：
    BN41694R
  • 中文名稱：
    Fas相關(guān)1因子抗體
  • 英文名稱：
    Rabbit anti-FAF1 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN41694R-50ul

    50ul

    ￥1486.00

    交叉反應(yīng)：Human,Rat(predicted:Mouse,Chicken,Dog,Cow,Rabbit) 推薦應(yīng)用：IHC-P,IHC-F,IF,ELISA

  • BN41694R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Rat(predicted:Mouse,Chicken,Dog,Cow,Rabbit) 推薦應(yīng)用：IHC-P,IHC-F,IF,ELISA

  • BN41694R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Rat(predicted:Mouse,Chicken,Dog,Cow,Rabbit) 推薦應(yīng)用：IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱FAF1
中文名稱Fas相關(guān)1因子抗體
別    名Fas associated factor 1; CGI; FAF1 protein; Fas (TNFRSF6) associated factor 1; FAS associated factor 1; FLJ37524; hFAF1; HFAF1s; Protein FAF1; CGI 03; FAF1; FAF1_HUMAN; Fas associated protein factor 1; FAS-associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A; UBXD12; UBXN3A; TNFRSF6 associated factor 1.  



研究領(lǐng)域細(xì)胞生物  免疫學(xué)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Rat,  (predicted: Mouse, Chicken, Dog, Cow, Rabbit, )
產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量74kDa
細(xì)胞定位細(xì)胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human FAF1:551-650/650 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated, Fas in both yeast and mammalian cells. It is transiently expressed in T cells and potentiates Fas-induced apoptosis. FAF1 lacks a DDH (Death domain homologous region), in contrast to TRADD, FADD, and RIP, and cannot induce apoptosis independent of Fas activation. Fas associated factor 1; CGI ; FAF1 protein; Fas (TNFRSF6) associated factor 1; FAS associated factor 1; FLJ37524; hFAF1; HFAF1s; Protein FAF1; TNFRSF6 associated factor 1.

Function:
Potentiates but cannot initiate FAS-induced apoptosis.

Subunit:
Specifically interacts with the cytoplasmic domain of FAS. Interacts with NLRP12 DAPIN/PYRIN domain via its UBA domain.

Subcellular Location:
Nucleus.

Tissue Specificity:
Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes.

Similarity:
Contains 1 UBA domain.
Contains 1 UBX domain.

SWISS:
Q9UNN5

Gene ID:
11124

Database links:

Entrez Gene: 11124 Human

Entrez Gene: 14084 Mouse

Entrez Gene: 140657 Rat

Omim: 604460 Human

SwissProt: Q9UNN5 Human

SwissProt: P54731 Mouse

SwissProt: Q924K2 Rat

Unigene: 530402 Human

Unigene: 318259 Mouse

Unigene: 198288 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.