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程序性死亡配體1抗體
  • 產品貨號：
    BN41619R
  • 中文名稱：
    程序性死亡配體1抗體
  • 英文名稱：
    Rabbit anti-PD-L1 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產品規(guī)格

    售價

    備注

  • BN41619R-50ul

    50ul

    ￥1486.00

    交叉反應：Human,Mouse,Rat(predicted:Pig,Cow,Horse,Sheep) 推薦應用：WB,ELISA

  • BN41619R-100ul

    100ul

    ￥2360.00

    交叉反應：Human,Mouse,Rat(predicted:Pig,Cow,Horse,Sheep) 推薦應用：WB,ELISA

  • BN41619R-200ul

    200ul

    ￥3490.00

    交叉反應：Human,Mouse,Rat(predicted:Pig,Cow,Horse,Sheep) 推薦應用：WB,ELISA

產品描述

英文名稱PD-L1
中文名稱程序性死亡配體1抗體
別    名CD274; B7 H; B7 H1; B7 homolog 1; B7-H1; B7H; B7H1; CD 274; CD274 antigen; CD274 molecule; MGC142294; MGC142296; OTTHUMP00000021029; PD L1; PD1L1_HUMAN; PD1L1_Mouse; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; PDL 1; PDL1; Programmed cell death 1 ligand 1; Programmed death ligand 1; RGD1566211.  
研究領域腫瘤  免疫學  細胞表面分子  細胞類型標志物  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse, Rat,  (predicted: Pig, Cow, Horse, Sheep, )
產品應用WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=1μg/Test 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量32kDa
細胞定位細胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human CD274:64-160/290 <Extracellular>
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產品介紹Programmed cell death 1 ligand 1(Programmed death ligand 1; PD-L1; PDCD1 ligand 1; B7 homolog 1; B7-H1; CD274) involved in the costimulatory signal, essential for T lymphocyte proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibit T-cell proliferation and cytokine production.

Function:
Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

Subunit:
Interacts with PDCD1.

Subcellular Location:
Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Endomembrane system; Single-pass type I membrane protein.

Tissue Specificity:
Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.

Similarity:
Belongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:
Q9EP73

Gene ID:
60533

Database links:

Entrez Gene: 29126 Human

Entrez Gene: 60533 Mouse

Entrez Gene: 499342 Rat

Omim: 605402 Human

SwissProt: Q9NZQ7 Human

SwissProt: Q9EP73 Mouse

Unigene: 521989 Human

Unigene: 245363 Mouse

Unigene: 228198 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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