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香葉烯基轉(zhuǎn)移酶1β抗體
  • 產(chǎn)品貨號：
    BN41382R
  • 中文名稱：
    香葉烯基轉(zhuǎn)移酶1β抗體
  • 英文名稱：
    Rabbit anti-PGGT1B Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

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  • BN41382R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Mouse,Rat(predicted:Human,Horse) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

  • BN41382R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Mouse,Rat(predicted:Human,Horse) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱PGGT1B
中文名稱香葉烯基轉(zhuǎn)移酶1β抗體
別    名PGGT1B; GGTase-I beta; GGTase-1 beta; BGGI; Geranylgeranyl transferase type I subunit beta; Geranylgeranyl transferase type-1 subunit beta; GGTase-I-beta; GGTI; PGGT1B; PGTB1_HUMAN; Type I protein geranyl-geranyltransferase subunit beta;   
研究領(lǐng)域細(xì)胞生物  免疫學(xué)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Mouse, Rat,  (predicted: Human, Horse, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量42kDa
細(xì)胞定位細(xì)胞核 細(xì)胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human PGGT1 beta:301-377/377 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]

Function:
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Acts on the Rac1, Rac2, Rap1A and Rap1B proteins. The beta subunit is responsible for peptide-binding.

Subunit:
Heterodimer of an alpha and a beta subunit.

Similarity:
Belongs to the protein prenyltransferase subunit beta family.
Contains 4 PFTB repeats.

SWISS:
P53609

Gene ID:
5229

Database links:

Entrez Gene: 5229 Human

Entrez Gene: 225467 Mouse

Entrez Gene: 81746 Rat

Omim: 602031 Human

SwissProt: P53609 Human

SwissProt: Q8BUY9 Mouse

SwissProt: P53610 Rat

Unigene: 254006 Human

Unigene: 262096 Mouse

Unigene: 393044 Mouse

Unigene: 10031 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications











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