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多胺調(diào)控因子1抗體

產(chǎn)品貨號：

BN41378R
中文名稱：

多胺調(diào)控因子1抗體
英文名稱：

Rabbit anti-NNF1R Polyclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規(guī)格

售價(jià)

備注
BN41378R-100ul

100ul

￥2360.00

交叉反應(yīng)：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Horse,Sheep) 推薦應(yīng)用：WB,IHC-P,ELISA
BN41378R-200ul

200ul

￥3490.00

交叉反應(yīng)：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Horse,Sheep) 推薦應(yīng)用：WB,IHC-P,ELISA

產(chǎn)品描述

英文名稱	NNF1R
中文名稱	多胺調(diào)控因子1抗體
別名	PMF-1; Pmf1; PMF1_HUMAN; NNF1R; Polyamine modulated factor 1; Polyamine-modulated factor 1.
研究領(lǐng)域	細(xì)胞生物信號轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白細(xì)胞分化表觀遺傳學(xué)
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, Rat, (predicted: Mouse, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	34kDa
細(xì)胞定位	細(xì)胞核
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human NNF1R/PMF1:101-200/300
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	NNF1R, also called PMF1, is part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. It is required for chromosome congression and for correct operation of the spindle checkpoint. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT. Function: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex. Subunit: Component of the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and CENPS. The CENPA-CAD complex interacts with the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and MLF1IP/CENPU. Subcellular Location: Nucleus. Associated with the kinetochore. SWISS: Q6P1K2 Gene ID: 11243 Database links: Entrez Gene: 100527963 Human Entrez Gene: 11243 Human Entrez Gene: 67037 Mouse Entrez Gene: 681050 Rat Omim: 609176 Human SwissProt: Q6P1K2 Human SwissProt: Q9CPV5 Mouse Unigene: 530479 Human Unigene: 654541 Human Unigene: 36715 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.