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尾側(cè)型同源轉(zhuǎn)錄因子2/3抗體
  • 產(chǎn)品貨號：
    BN41372R
  • 中文名稱：
    尾側(cè)型同源轉(zhuǎn)錄因子2/3抗體
  • 英文名稱：
    Rabbit anti-CDX2+3 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN41372R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human(predicted:Mouse,Rat,Chicken,Pig,Cow,Horse) 推薦應(yīng)用：IHC-P,IHC-F,IF,ELISA

  • BN41372R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human(predicted:Mouse,Rat,Chicken,Pig,Cow,Horse) 推薦應(yīng)用：IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱CDX2+3
中文名稱尾側(cè)型同源轉(zhuǎn)錄因子2/3抗體
別    名Caudal type homeo box 2; Caudal type homeo box transcription factor 2; Caudal type homeobox 2; Caudal type homeobox protein 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX 2; CDX 3; CDX-3; Cdx2; CDX2_HUMAN; CDX3; CDX2+3; Homeobox protein CDX 2; Homeobox protein CDX-2.  
研究領(lǐng)域腫瘤  細胞生物  發(fā)育生物學(xué)  信號轉(zhuǎn)導(dǎo)  干細胞  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human,  (predicted: Mouse, Rat, Chicken, Pig, Cow, Horse, )
產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量34kDa
細胞定位細胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human CDX2/3:151-260/313 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012].

Function:
Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylation of Ser-60 mediates the transactivation capacity.

Similarity:
Belongs to the Caudal homeobox family.
Contains 1 homeobox DNA-binding domain.

SWISS:
Q99626

Gene ID:
1045

Database links:

Entrez Gene: 1045 Human

Entrez Gene: 12591 Mouse

Entrez Gene: 66019 Rat

Omim: 600297 Human

SwissProt: Q99626 Human

SwissProt: P43241 Mouse

Unigene: 174249 Human

Unigene: 20358 Mouse

Unigene: 64495 Ra



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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