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核通道蛋白SEH1L抗體
  • 產(chǎn)品貨號(hào)：
    BN41350R
  • 中文名稱：
    核通道蛋白SEH1L抗體
  • 英文名稱：
    Rabbit anti-SEH1L Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號(hào)

    產(chǎn)品規(guī)格

    售價(jià)

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  • BN41350R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Rat(predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Rabbit) 推薦應(yīng)用：IHC-P,IHC-F,ICC,IF,ELISA

  • BN41350R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Rat(predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Rabbit) 推薦應(yīng)用：IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱SEH1L
中文名稱核通道蛋白SEH1L抗體
別    名Nucleoporin SEH1; Nup107-160 subcomplex subunit SEH1; SEC13-like protein; SEC13L; Seh 1; SEH1-like (S. cerevisiae); SEH1_HUMAN; SEH1A; SEH1B; SEH1L  
研究領(lǐng)域細(xì)胞生物  免疫學(xué)  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Rat,  (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Rabbit, )
產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量40kDa
細(xì)胞定位細(xì)胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SEH1L:1-100/360 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Seh1 is a 421 amino acid protein belonging to the WD repeat Sec13 family. Localized to the nucleus, Seh1 is a component of the nuclear pore complex Nup107-160. Nuclear pore complexes control bidirectional transport of macromolecules between the cytoplasm and the nucleus. All components of the complex Nup107-160, including Seh1, localize to the kinetochores during mitosis. Seh1 is expressed as two isoforms produced by alternative splicing and contains six WD repeats.

Function:
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.

Subcellular Location:
Chromosome; centromere; kinetochore. Nucleus; nuclear pore complex.

Similarity:
Belongs to the WD repeat SEC13 family.
Contains 6 WD repeats.

SWISS:
Q96EE3

Gene ID:
81929

Database links:

Entrez Gene: 81929 Human

Omim: 609263 Human

SwissProt: Q96EE3 Human

Unigene: 301048 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.