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CSMD2蛋白抗體
  • 產(chǎn)品貨號：
    BN41306R
  • 中文名稱：
    CSMD2蛋白抗體
  • 英文名稱：
    Rabbit anti-CSMD2 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

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  • BN41306R-100ul

    100ul

    ￥2360.00

    交叉反應：Rat,Mouse(predicted:Sheep,Horse,Cow,Dog,Chicken,Human) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN41306R-200ul

    200ul

    ￥3490.00

    交叉反應：Rat,Mouse(predicted:Sheep,Horse,Cow,Dog,Chicken,Human) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱CSMD2
中文名稱CSMD2蛋白抗體
別    名CSMD2_HUMAN; CUB and Sushi (SCR repeat) domain; CUB and sushi domain-containing protein 2; CUB and sushi multiple domains protein 2; dJ1007G16.1; dJ1007G16.2; dJ947L8.1; KIAA1884.  
研究領域細胞生物  免疫學  神經(jīng)生物學  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Mouse,  (predicted: Human, Rat, Chicken, Dog, Cow, Horse, Sheep, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量380kDa
細胞定位細胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human CSMD2:251-350/3487 <Extracellular>
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The CUB and sushi domain-containing proteins, CSMD1-3, are membrane proteins that are involved in cell-cell adhesion and are weakly expressed in most tissues, with higher levels of expression observed in the cerebellum and hippocampus. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas. CSMD2 and CSMD3 are located primarily in the brain and are implicated in some forms of head and neck cancer. Additionally, the CSMD3 gene is a candidate for induction of epileptic seizures.

Subcellular Location:
Cell membrane; Single-pass membrane protein (Potential).

Tissue Specificity:
Weakly expressed in most tissues, except in brain. Expressed at intermediate level in brain, including cerebellum, substantia nigra, hippocampus and fetal brain. Overexpressed in some head and neck cancer cell lines.

Similarity:
Belongs to the CSMD family.
Contains 14 CUB domains.
Contains 26 Sushi (CCP/SCR) domains.

SWISS:
Q7Z408

Gene ID:
114784

Database links:

Entrez Gene: 114784 Human

Omim: 608398 Human

SwissProt: Q7Z408 Human

Unigene: 656915 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.