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磷酸化Rho GTP酶激活蛋白GAP抗體
  • 產(chǎn)品貨號：
    BN41273R
  • 中文名稱：
    磷酸化Rho GTP酶激活蛋白GAP抗體
  • 英文名稱：
    Rabbit anti-phospho-RACGAP1 (Ser387) Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN41273R-100ul

    100ul

    ￥2470.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Dog,Cow) 推薦應(yīng)用：WB,ELISA

產(chǎn)品描述

英文名稱phospho-RACGAP1 (Ser387)
中文名稱磷酸化Rho GTP酶激活蛋白GAP抗體
別    名RACGAP1 (phospho S387); p-RACGAP1(S387); p-RACGAP1(Ser387); GAP; Gap1; GTPase activating protein; HsCYK 4; HsCYK4; ID GAP; KIAA1478; MgcRacGAP; Rac GTPase activating protein 1; RACGAP 1.  
產(chǎn)品類型磷酸化抗體 
研究領(lǐng)域細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  細(xì)胞分化  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse,  (predicted: Rat, Dog, Cow, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量71kDa
細(xì)胞定位細(xì)胞核 細(xì)胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthesised phosphopeptide derived from human RACGAP1 around the phosphorylation site of Ser387:RI(p-S)GC 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.

Subunit:
Heterotetramer of two molecules each of RACGAP1 and KIF23.

Subcellular Location:
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle.

Tissue Specificity:
Highly expressed in testis, thymus and placenta. Expressed at lower levels in spleen and peripheral blood lymphocytes. In testis, expression is restricted to germ cells with the highest levels of expression found in spermatocytes. Expression is regulated in a cell cycle-dependent manner and peaks during G2/M phase.

Similarity:
Contains 1 phorbol-ester/DAG-type zinc finger. Contains 1 Rho-GAP domain.

SWISS:
Q9H0H5

Gene ID:
29127

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
















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