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上游結(jié)合蛋白1抗體
  • 產(chǎn)品貨號：
    BN41230R
  • 中文名稱：
    上游結(jié)合蛋白1抗體
  • 英文名稱：
    Rabbit anti-Upstream Binding Protein 1 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

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  • BN41230R-100ul

    100ul

    ￥2360.00

    交叉反應：Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse) 推薦應用：WB,ELISA

  • BN41230R-200ul

    200ul

    ￥3490.00

    交叉反應：Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse) 推薦應用：WB,ELISA

產(chǎn)品描述

英文名稱Upstream Binding Protein 1
中文名稱上游結(jié)合蛋白1抗體
別    名LBP 1a; Cp2b; DKFZp686L1745; LBP 1a; LBP 1B; LBP1; LBP1A; LBP1B; NF2d9; Upstream binding protein 1; Transcription factor LBP-1; UBIP1_HUMAN.  
研究領域腫瘤  細胞生物  信號轉(zhuǎn)導  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  表觀遺傳學  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量60kDa
細胞定位細胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Upstream Binding Protein 1:351-450/540 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.

Function:
UBP1 is an important SF1 independent transcriptional activator stimulating P450scc expression in human placental JEG 3 cells.

Subunit:
Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines.

Similarity:
Belongs to the grh/CP2 family. CP2 subfamily.

SWISS:
Q9NZI7

Gene ID:
7342

Database links:

Entrez Gene: 7342 Human

Entrez Gene: 22221 Mouse

Entrez Gene: 301038 Rat

Omim: 609784 Human

SwissProt: Q86Y57 Human

SwissProt: Q9NZI7 Human

SwissProt: Q60786 Mouse

SwissProt: Q811S7 Mouse

SwissProt: Q8BH21 Mouse

Unigene: 118041 Human

Unigene: 729120 Human

Unigene: 28052 Mouse

Unigene: 386808 Mouse

Unigene: 15705 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.














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