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G蛋白激活內(nèi)向鉀通道1抗體
  • 產(chǎn)品貨號：
    BN41224R
  • 中文名稱：
    G蛋白激活內(nèi)向鉀通道1抗體
  • 英文名稱：
    Rabbit anti-GIRK1/KCNJ3 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN41224R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Rabbit,GuineaPig) 推薦應(yīng)用：WB,ELISA

  • BN41224R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Rabbit,GuineaPig) 推薦應(yīng)用：WB,ELISA

產(chǎn)品描述

英文名稱GIRK1/KCNJ3
中文名稱G蛋白激活內(nèi)向鉀通道1抗體
別    名inwardly rectifying subfamily J member 3; G protein activated inward rectifier potassium channel 1; G protein-activated inward rectifier potassium channel 1; GIRK-1; Inward rectifier K(+) channel Kir3.1; Inwardly rectifying potassium channel KIR3.1; IRK3; IRK3_HUMAN; Kcnf3; Kcnj3; KGA; KGB1; Kir3.1; Potassium channel; Potassium channel, inwardly rectifying subfamily J member 3; Potassium inwardly-rectifying channel, subfamily J, member 3.  




研究領(lǐng)域細(xì)胞生物  神經(jīng)生物學(xué)  通道蛋白  細(xì)胞膜受體  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Rabbit, Guinea Pig, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量55kDa
細(xì)胞定位細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GIRK1:81-180/501 <Extracellular>
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

Function:
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

Subunit:
Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.

SWISS:
P48549

Gene ID:
3760

Database links:

Entrez Gene: 3760 Human

Entrez Gene: 16519 Mouse

Entrez Gene: 50599 Rat

Omim: 601534 Human

SwissProt: P48549 Human

SwissProt: P63250 Mouse

SwissProt: P63251 Rat

Unigene: 591606 Human

Unigene: 5127 Mouse

Unigene: 9809 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.














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