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蛋白質(zhì)磷酸酶2A亞基3抗體
  • 產(chǎn)品貨號：
    BN41167R
  • 中文名稱：
    蛋白質(zhì)磷酸酶2A亞基3抗體
  • 英文名稱：
    Rabbit anti-PPP2R3 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN41167R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Mouse,Rat(predicted:Human,Dog,Horse,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

  • BN41167R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Mouse,Rat(predicted:Human,Dog,Horse,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱PPP2R3
中文名稱蛋白質(zhì)磷酸酶2A亞基3抗體
別    名AI118493; DNA for thyroid hormone receptor binding site (258bp); P2R3A_HUMAN; PP2A subunit B B72/B130 isoforms; PP2A subunit B isoform PR72/PR130; PP2A subunit B isoform R3 isoform; PP2A subunit B isoforms B72/B130; PP2A subunit B PR72/PR130 isoforms; PP2A subunit B R3 isoform; Ppp2r3a; PR130; PR59; PR72; Serine/threonine protein phosphatase 2A 72/130 kDa regulatory subunit B; Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B.   
研究領(lǐng)域腫瘤  細胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細胞周期蛋白  激酶和磷酸酶  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Mouse, Rat,  (predicted: Human, Dog, Horse, Rabbit, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量130kDa
細胞定位細胞核 細胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human PPP2R3:801-900/1150 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Function:
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Subunit:
PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules.

Tissue Specificity:
Expressed in heart, brain, placenta, lung, muscle and kidney.

Similarity:
Contains 2 EF-hand domains.

SWISS:
Q06190

Gene ID:
5523

Database links:

Entrez Gene: 5523 Human

Omim: 604944 Human

SwissProt: Q06190 Human

Unigene: 518155 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.