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N-鈣粘附分子抗體
  • 產(chǎn)品貨號(hào)：
    BN41119R
  • 中文名稱：
    N-鈣粘附分子抗體
  • 英文名稱：
    Rabbit anti-N-Cadherin Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN41119R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat) 推薦應(yīng)用：WB,ELISA

  • BN41119R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat) 推薦應(yīng)用：WB,ELISA

產(chǎn)品描述

英文名稱N-Cadherin
中文名稱N-鈣粘附分子抗體
別    名Cadherin 2; Cadherin 2 N cadherin neuronal; Cadherin 2 type 1; Cadherin 2 type 1 N cadherin neuronal; cadherin 2 type 1 N-cadherin neuronal; Cadherin2; Calcium dependent adhesion protein neuronal; CD325; CD325 antigen; CDH2; CDHN; CDw325; CDw325 antigen; N cadherin 1; NCAD; Neural Cadherin; Neural Cadherin.  
研究領(lǐng)域腫瘤  細(xì)胞生物  免疫學(xué)  激酶和磷酸酶  細(xì)胞粘附分子  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse,  (predicted: Rat, )
產(chǎn)品應(yīng)用WB=1:500-1000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量97/99kDa
細(xì)胞定位細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human N-Cadherin:750-850-905 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMedPubMed
產(chǎn)品介紹This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

Function:
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.

Subcellular Location:
Cell membrane.

Similarity:
Contains 5 cadherin domains.

SWISS:
P19022

Gene ID:
1000

Database links:

Entrez Gene: 1000 Human

Entrez Gene: 281062 Cow

Entrez Gene: 12558 Mouse

Entrez Gene: 83501 Rat

Omim: 114020 Human

SwissProt: P19022 Human

SwissProt: P15116 Mouse

SwissProt: Q9Z1Y3 Rat

Unigene: 464829 Human

Unigene: 606106 Human

Unigene: 257437 Mouse

Unigene: 23200 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

細(xì)胞粘附蛋白（Call Adhesion Protein） N-鈣粘附分子屬于依賴鈣離子的細(xì)胞間糖蛋白粘附分子的一部分,主要是參與細(xì)胞間同源性粘附,調(diào)控和介導(dǎo)細(xì)胞間相互反應(yīng)。