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Bcl-2結(jié)合抑凋亡蛋白2抗體
  • 產(chǎn)品貨號(hào)：
    BN41044R
  • 中文名稱：
    Bcl-2結(jié)合抑凋亡蛋白2抗體
  • 英文名稱：
    Rabbit anti-BAG2 Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN41044R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Horse) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41044R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Horse) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱BAG2
中文名稱Bcl-2結(jié)合抑凋亡蛋白2抗體
別    名BAG 2; BAG-2; BAG family molecular chaperone regulator 2; BAG-2; Bag2; BAG2_HUMAN; BCL 2 associated athanogene 2; Bcl-2-associated athanogene 2; BCL2 associated athanogene 2; dJ417I1.2; KIAA0576; MGC149462.  
研究領(lǐng)域腫瘤  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Horse, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量24kDa
細(xì)胞定位細(xì)胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human BAG2:151-211/211 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq].

Function:
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.

Similarity:
Contains 1 BAG domain.

SWISS:
O95816

Gene ID:
9532

Database links:

Entrez Gene: 9532 Human

Omim: 603882 Human

SwissProt: O95816 Human

Unigene: 55220 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.










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