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含錨蛋白重復(fù)序列-細胞因子信號抑制物盒蛋白家族10抗體
  • 產(chǎn)品貨號：
    BN41016R
  • 中文名稱：
    含錨蛋白重復(fù)序列-細胞因子信號抑制物盒蛋白家族10抗體
  • 英文名稱：
    Rabbit anti-ASB10 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

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  • BN41016R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

  • BN41016R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱ASB10
中文名稱含錨蛋白重復(fù)序列-細胞因子信號抑制物盒蛋白家族10抗體
別    名Ankyrin repeat and SOCS box containing 10; Ankyrin repeat and SOCS box protein 10; ASB 10; ASB-10; ASB10; ASB10_HUMAN.  
研究領(lǐng)域細胞生物  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量51kDa
細胞定位細胞核 細胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ASB10.:401-450/467 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹ASB10 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling (SOCS) family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box couples the suppressor of cytokine signalling proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation.

Function:
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

Similarity:
Contains 7 ANK repeats.
Contains 1 SOCS box domain.

SWISS:
Q8WXI3

Gene ID:
136371

Database links:

Entrez Gene: 136371 Human

Omim: 615054 Human

SwissProt: Q8WXI3 Human

Unigene: 647081 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.










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