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硒結(jié)合蛋白1抗體
  • 產(chǎn)品貨號：
    BN41003R
  • 中文名稱：
    硒結(jié)合蛋白1抗體
  • 英文名稱：
    Rabbit anti-Selenium Binding Protein 1 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

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  • BN41003R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Cow,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN41003R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Cow,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱Selenium Binding Protein 1
中文名稱硒結(jié)合蛋白1抗體
別    名56 kDa selenium binding protein; 56 kDa selenium-binding protein; hSBP; LPSB; SBP; SBP1; SBP1_HUMAN; SBP56; Selenbp1; Selenbp2; Selenium binding protein 2; Selenium binding protein1; Selenium-binding protein 1; SELNBP1; SP56.  
研究領(lǐng)域腫瘤  免疫學(xué)  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse, Rat,  (predicted: Dog, Cow, Rabbit, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量52kDa
細胞定位細胞核 細胞漿 細胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SBP1/Selenium Binding Protein 1:401-472/472 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Selenium is an essential trace element that confers tolerance to toxicity arising through exposure to heavy metals or other reactive xenobiotics. Selenium exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. Both effects are attributed to selenium-binding proteins. Selenium binding protein 1 is down-regulated in lung adenocarcinoma, colorectal cander and ovarian cancer. It is two-fold upregulated in the brains of patients suffering from schizophrenia, and is therefore a biomarker for this disease.

Function:
Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.

Subunit:
Interacts with USP33.

Subcellular Location:
Nucleus. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=May associate with Golgi membrane. May associate with the membrane of autophagosomes.

Tissue Specificity:
Present in liver and colon (at protein level).

Post-translational modifications:
The N-terminus is blocked.

Similarity:
Belongs to the selenium-binding protein family.

SWISS:
Q13228

Gene ID:
8991

Database links:

Entrez Gene: 8991 Human

Entrez Gene: 20341 Mouse

Entrez Gene: 140927 Rat

Omim: 604188 Human

SwissProt: Q13228 Human

SwissProt: P17563 Mouse

SwissProt: Q8VIF7 Rat

Unigene: 632460 Human

Unigene: 16617 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.