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肌紅蛋白抗體
  • 產(chǎn)品貨號(hào)：
    BN40994R
  • 中文名稱：
    肌紅蛋白抗體
  • 英文名稱：
    Rabbit anti-Myoglobin Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN40994R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse,Rat 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40994R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse,Rat 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱Myoglobin
中文名稱肌紅蛋白抗體
別    名MYO; MB; MGC13548; PVALB; MYG_HUMAN.  
研究領(lǐng)域腫瘤  心血管  細(xì)胞生物  免疫學(xué)  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse, Rat, 
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量17kDa
細(xì)胞定位細(xì)胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原Purified Human Myoglobin (Natural Human Myoglobin protein): 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Myoglobin is a small heme containing protein responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.

Function:
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Similarity:
Belongs to the globin family.

SWISS:
P02144

Gene ID:
4151

Database links:

Entrez Gene: 4151 Human

Entrez Gene: 17189 Mouse

Entrez Gene: 59108 Rat

Omim: 160000 Human

SwissProt: P02144 Human

SwissProt: P04247 Mouse

SwissProt: Q9QZ76 Rat

Unigene: 517586 Human

Unigene: 404074 Mouse

Unigene: 40511 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

肌紅蛋白存在于肌肉中，心肌中含量特別豐富，，有較高的組織特異性，是橫紋肌的特異性標(biāo)記物，但對(duì)腫瘤的敏感性較差。主要用于橫紋肌腫瘤的診斷與鑒別診斷。少數(shù)惡性中胚葉混合瘤、睪丸畸胎瘤、腎母細(xì)胞瘤亦可見(jiàn)陽(yáng)性表達(dá)。