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草酰琥珀酸脫羧酶α抗體
  • 產(chǎn)品貨號：
    BN40982R
  • 中文名稱：
    草酰琥珀酸脫羧酶α抗體
  • 英文名稱：
    Rabbit anti-IDH3A Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

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  • BN40982R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human(predicted:Mouse,Rat,Pig,Cow,Horse,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

  • BN40982R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human(predicted:Mouse,Rat,Pig,Cow,Horse,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱IDH3A
中文名稱草酰琥珀酸脫羧酶α抗體
別    名EC 1.1.1.41; H IDH alpha; HIDH alpha; Isocitrate dehydrogenase (NAD+) alpha chain precursor; Isocitrate dehydrogenase [NAD] subunit alpha mitochondrial; Isocitrate dehydrogenase 3 (NAD+) alpha; Isocitrate dehydrogenase; Isocitric dehydrogenase; NAD; NAD(H) specific isocitrate dehydrogenase alpha subunit precursor; NAD+ specific ICDH; NADsubunit alpha mitochondrial precursor.  



研究領(lǐng)域腫瘤  細胞生物  免疫學(xué)  染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human,  (predicted: Mouse, Rat, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量37kDa
細胞定位細胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human IDH3A:281-366/366 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. IDH3A is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

Subunit:
Heterooligomer of subunits alpha, beta, and gamma in the apparent ratio of 2:1:1.

Subcellular Location:
Mitochondrion.

Similarity:
Belongs to the isocitrate and isopropylmalate dehydrogenases family.

SWISS:
P50213

Gene ID:
3419

Database links:

Entrez Gene: 3419 Human

Entrez Gene: 67834 Mouse

Entrez Gene: 114096 Rat

Omim: 601149 Human

SwissProt: P50213 Human

SwissProt: Q9D6R2 Mouse

SwissProt: Q99NA5 Rat

Unigene: 591110 Human

Unigene: 279195 Mouse

Unigene: 95104 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











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