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胚胎干細胞關鍵蛋白190抗體(N端)
  • 產(chǎn)品貨號：
    BN40969R
  • 中文名稱：
    胚胎干細胞關鍵蛋白190抗體(N端)
  • 英文名稱：
    Rabbit anti-Oct-4B/OCT4B-190 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN40969R-100ul

    100ul

    ￥2360.00

    交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow) 推薦應用：WB,IHC-P,Flow-Cyt,ELISA

  • BN40969R-200ul

    200ul

    ￥3490.00

    交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow) 推薦應用：WB,IHC-P,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱Oct-4B/OCT4B-190
中文名稱胚胎干細胞關鍵蛋白190抗體(N端)
別    名Oct-4B; Oct4B; Oct 4B; Oct 4B-190; Oct4B-190; POU domain, class 5, transcription factor 1; Octamer-binding transcription factor 3; Oct-3; NF-A3; Otf-3; Otf3; POU5F1.  
研究領域腫瘤  細胞生物  免疫學  干細胞  轉錄調(diào)節(jié)因子  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 Flow-Cyt=1μg /Test （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量21/39kDa
細胞定位細胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human OCT4B-190:201-300/360 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq].

SWISS:
Q01860

Gene ID:
5460

Database links:

Entrez Gene: 5460 Human

Entrez Gene: 18999 Mouse

Entrez Gene: 294562 Rat

Omim: 164177 Human

SwissProt: Q01860 Human

SwissProt: P20263 Mouse

Unigene: 249184 Human

Unigene: 632482 Human

Unigene: 646545 Human

Unigene: 17031 Mouse

Unigene: 161748 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

OCT4B-190蛋白能夠增強細胞在應激條件下抵抗凋亡的能力。OCT4基因在干細胞的增殖、分化、應激反應、凋亡過程等多個生物學過程中發(fā)揮著重要的作用。