最近搜索：細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué)
首頁>>免疫學(xué)>>一抗>>磷酸化蛋白激酶GCN2蛋白抗體
磷酸化蛋白激酶GCN2蛋白抗體
  • 產(chǎn)品貨號：
    BN40868R
  • 中文名稱：
    磷酸化蛋白激酶GCN2蛋白抗體
  • 英文名稱：
    Rabbit anti-phospho-GCN2 (Thr667) Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN40868R-100ul

    100ul

    ￥2470.00

    交叉反應(yīng)：Mouse,Rat(predicted:Human,Dog,Cow,Horse) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱phospho-GCN2 (Thr667)
中文名稱磷酸化蛋白激酶GCN2蛋白抗體
別    名GCN2 (phospho T667); p-GCN2 (phospho T667); EIF2AK4; Eukaryotic Translation Initiation Factor 2-alpha kinase 4; GCN2-like protein; KIAA1338; E2AK4_HUMAN; Eif2ak4; Eukaryotic Translation Initiation Factor 2 alpha kinase 4; GCN2; GCN2 eIF2alpha kinase; GCN2-like protein; MGCN2.  
產(chǎn)品類型磷酸化抗體 
研究領(lǐng)域細(xì)胞生物  神經(jīng)生物學(xué)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Mouse, Rat,  (predicted: Human, Dog, Cow, Horse, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量181kDa
細(xì)胞定位細(xì)胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated Synthesised phosphopeptide derived from human GCN2 around the phosphorylation site of Thr667:PG(p-T)PP 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹GCN2 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor 2 to downregulate protein synthesis in response to varied cellular stresses.

Tissue Specificity:
Widely expressed.

Post-translational modifications:
Autophosphorylated on threonine residues.

Similarity:
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.
Contains 2 protein kinase domains.
Contains 1 RWD domain.

SWISS:
Q9P2K8

Gene ID:
440275

Database links:

Entrez Gene: 440275 Human

Entrez Gene: 27103 Mouse

Entrez Gene: 114859 Rat

Omim: 609280 Human

SwissProt: Q9P2K8 Human

SwissProt: Q9QZ05 Mouse

Unigene: 656673 Human

Unigene: 217616 Mouse

Unigene: 8333 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

GCN2蛋白的作用；可能是將短期記憶變成長期記憶的一個主控調(diào)節(jié)因子， GCN2蛋白在長期記憶形成中功能的發(fā)現(xiàn)將可能幫助研究人員開發(fā)出提高記憶力喪失的病人提高記憶力。