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CD90抗體
  • 產(chǎn)品貨號：
    BN40618R
  • 中文名稱：
    CD90抗體
  • 英文名稱：
    Rabbit anti-CD90 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

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  • BN40618R-100ul

    100ul

    ￥2360.00

    交叉反應：Human,Mouse(predicted:Rat) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN40618R-200ul

    200ul

    ￥3490.00

    交叉反應：Human,Mouse(predicted:Rat) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱CD90
中文名稱CD90抗體
別    名CD90 / Thy1; CD7; CD90 antigen; CDw90; FLJ33325; MGC128895; T25; Theta antigen; Thy-1; Thy 1; Thy 1 cell surface antigen; Thy 1 membrane glycoprotein; Thy 1 membrane glycoprotein precursor; Thy 1.2; Thy-1 T-cell antigen; Thy1 antigen; Thy1 T cell antigen; Thy1.1; Thy1.2; Thymus cell antigen 1, theta; THY1_RAT; THY1_HUMAN.  



研究領域細胞生物  免疫學  神經(jīng)生物學  t-淋巴細胞  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse,  (predicted: Rat, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量12kDa
細胞定位細胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human CD90:20-100/161 <Extracellular>
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Thy-1 or CD90 (Cluster of Differentiation 90) is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. Thy-1can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of Thy-1 lead to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to some of the initial biochemical description and characterization of a vertebrate GPI anchor and also the first demonstration of tissue specific differential glycosylation.

Function:
May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor.

Tissue Specificity:
Abundant in lymphoid tissues.

Post-translational modifications:
Glycosylation is tissue specific. Sialylation of N-glycans at Asn-93 in brain and at Asn-42, Asn-93 and Asn-117 in thymus.

Similarity:
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:
P04216

Gene ID:
7070

Database links:

Entrez Gene: 7070 Human

Entrez Gene: 21838 Mouse

Entrez Gene: 24832 Rat

Omim: 188230 Human

SwissProt: P04216 Human

SwissProt: P01831 Mouse

SwissProt: P01830 Rat

Unigene: 644697 Human

Unigene: 3951 Mouse

Unigene: 108198 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Thy1/CD90主要表達于腦和淋巴組織，包括胸腺細胞、外周血液T細胞和一些上皮內(nèi)層T細胞。
Thy-1是一種糖基磷酸酯酰醇（GPI）固定的表面糖蛋白，Thy-1在T細胞激活、神經(jīng)系統(tǒng)發(fā)育及其發(fā)揮功能、細胞程序性死亡等方面發(fā)揮作用。