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氯離子通道蛋白6抗體
  • 產(chǎn)品貨號：
    BN40346R
  • 中文名稱：
    氯離子通道蛋白6抗體
  • 英文名稱：
    Rabbit anti-CLIC6 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN40346R-100ul

    100ul

    ￥2360.00

    交叉反應：Human,Mouse(predicted:Rat,Dog,Pig,Cow,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN40346R-200ul

    200ul

    ￥3490.00

    交叉反應：Human,Mouse(predicted:Rat,Dog,Pig,Cow,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

產(chǎn)品描述

英文名稱CLIC6
中文名稱氯離子通道蛋白6抗體
別    名Chloride channel form A; Chloride intracellular channel 6; Chloride intracellular channel protein 6; CLIC1L; Clic6; CLIC6_HUMAN; Parchorin.   
研究領域腫瘤  神經(jīng)生物學  通道蛋白  細胞膜受體  G蛋白偶聯(lián)受體  新陳代謝  G蛋白信號  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量73kDa
細胞定位細胞漿 細胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human CLIC6:531-630/704 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹CLIC6 (chloride intracellular channel 6) is believed to play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport. The CLIC6 gene is a rare example of large-scale segmental paralogy in which a large (approximately 500 kb) segment on human chromosome (HC) 21 (21q22) is triplicated on HC 1 and HC 6. CLIC6 is also known to interact with dopamine receptors DRD2, DRD3 and DRD4. CLIC6 is primarily expressed in the cytoplasm, however, upon chloride ion efflux from the cell, CLIC6 is translocated to the plasma membrane. CLIC6 has been identified in brain, placenta, pancreas and liver.

Function:
May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport.

Subunit:
Interacts with dopamine receptors DRD2, DRD3 and DRD4

Subcellular Location:
Cytoplasm. Cell membrane. Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane.

Tissue Specificity:
Expressed in brain, placenta, pancreas and liver.

Post-translational modifications:
Phosphorylated.

Similarity:
Belongs to the chloride channel CLIC family.
Contains 1 GST C-terminal domain.

SWISS:
Q96NY7

Gene ID:
54102

Database links:

Entrez Gene: 54102 Human

Omim: 615321 Human

SwissProt: Q96NY7 Human

Unigene: 473695 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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